LymphedemaV1, Main, Exploration, bibRecord, 000549

First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination

Identifieur interne : 000549 ( Main/Exploration ); précédent : 000548; suivant : 000550

First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination

Auteurs : Hugues C. Nana-Djeunga [Cameroun] ; Magellan Tchouakui [Cameroun] ; Guy R. Njitchouang [Cameroun] ; Jules B. Tchatchueng-Mbougua [Cameroun] ; Philippe Nwane [Cameroun] ; André Domche [Cameroun] ; Jean Bopda [Cameroun] ; Stève Mbickmen-Tchana [Cameroun] ; Julie Akame [Cameroun] ; Ann Tarini [Cameroun] ; Emilienne Epée [Cameroun] ; Benjamin D. Biholong [Cameroun] ; Yaobi Zhang [Sénégal] ; Jean J. Tougoue [États-Unis] ; Achille Kabore [États-Unis] ; Flobert Njiokou [Cameroun] ; Joseph Kamgno [Cameroun]

Source :

PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2017.

RBID : PMC:5490934

Descripteurs français

KwdFr :
- Administration des services de santé, Albendazole (administration et posologie), Animaux, Antigènes d'helminthe (sang), Cameroun (épidémiologie), Contrôle des maladies contagieuses (), Enfant, Enfant d'âge préscolaire, Femelle, Filaricides (administration et posologie), Filariose lymphatique (), Filariose lymphatique (transmission), Filariose lymphatique (épidémiologie), Humains, Immunochromatographie, Ivermectine (administration et posologie), Mâle, Transmission de maladie infectieuse (), Wuchereria bancrofti (isolement et purification), Éradication de maladie.
MESH :
- administration et posologie : Albendazole, Filaricides, Ivermectine.
- isolement et purification : Wuchereria bancrofti.
- sang : Antigènes d'helminthe.
- épidémiologie : Cameroun, Filariose lymphatique.
- Administration des services de santé, Animaux, Contrôle des maladies contagieuses, Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique, Humains, Immunochromatographie, Mâle, Transmission de maladie infectieuse, Éradication de maladie.

English descriptors

KwdEn :
- Albendazole (administration & dosage), Animals, Antigens, Helminth (blood), Cameroon (epidemiology), Child, Child, Preschool, Communicable Disease Control (methods), Disease Eradication, Disease Transmission, Infectious (prevention & control), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (prevention & control), Elephantiasis, Filarial (transmission), Female, Filaricides (administration & dosage), Health Services Administration, Humans, Immunochromatography, Ivermectin (administration & dosage), Male, Wuchereria bancrofti (isolation & purification).
MESH :
- chemical , administration & dosage : Albendazole, Filaricides, Ivermectin.
- chemical , blood : Antigens, Helminth.
- epidemiology : Cameroon, Elephantiasis, Filarial.
- isolation & purification : Wuchereria bancrofti.
- methods : Communicable Disease Control.
- prevention & control : Disease Transmission, Infectious, Elephantiasis, Filarial.
- transmission : Elephantiasis, Filarial.
- Animals, Child, Child, Preschool, Disease Eradication, Female, Health Services Administration, Humans, Immunochromatography, Male.

Abstract

Background

Lymphatic filariasis (LF) is among the 10 neglected tropical diseases targeted for control or elimination by 2020. For LF elimination, the World Health Organization (WHO) has proposed a comprehensive strategy including (i) interruption of LF transmission through large-scale annual treatment (or mass drug administration (MDA)) of all eligible individuals in endemic areas, and (ii) alleviation of LF-associated suffering through morbidity management and disability prevention. In Cameroon, once-yearly mass administration of ivermectin and albendazole has been implemented since 2008. The aim of this study was to assess progress towards the elimination goal, looking specifically at the impact of six rounds of MDA on LF transmission in northern Cameroon.

Methodology

The study was conducted in the North and Far North Regions of Cameroon. Five health districts that successfully completed six rounds of MDA (defined as achieving a treatment coverage ≥ 65% each year) and reported no positive results for Wuchereria bancrofti microfilariaemia during routine surveys following the fifth MDA were grouped into three evaluation units (EU) according to WHO criteria. LF transmission was assessed through a community-based transmission assessment survey (TAS) using an immunochromatographic test (ICT) for the detection of circulating filarial antigen (CFA) in children aged 5–8 years old.

Principal findings

A total of 5292 children (male/female ratio 1.04) aged 5–8 years old were examined in 97 communities. Positive CFA results were observed in 2, 8 and 11 cases, with a CFA prevalence of 0.13% (95% CI: 0.04–0.46) in EU#1, 0.57% (95% CI: 0.32–1.02) in EU#2, and 0.45% (95% CI: 0.23–0.89) in EU#3.

Conclusion/Significance

The positive CFA cases were below WHO defined critical cut-off thresholds for stopping treatment and suggest that transmission can no longer be sustained. Post-MDA surveillance activities should be organized to evaluate whether recrudescence can occur.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490934

DOI: 10.1371/journal.pntd.0005633
PubMed: 28662054
PubMed Central: 5490934

Affiliations:

Cameroun, Sénégal, États-Unis

Le document en format XML

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<author><name sortKey="Bopda, Jean" sort="Bopda, Jean" uniqKey="Bopda J" first="Jean" last="Bopda">Jean Bopda</name>
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</author>
<author><name sortKey="Mbickmen Tchana, Steve" sort="Mbickmen Tchana, Steve" uniqKey="Mbickmen Tchana S" first="Stève" last="Mbickmen-Tchana">Stève Mbickmen-Tchana</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Centre for Research on Filariasis and other Tropical Diseases, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Centre for Research on Filariasis and other Tropical Diseases, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Akame, Julie" sort="Akame, Julie" uniqKey="Akame J" first="Julie" last="Akame">Julie Akame</name>
<affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Helen Keller International, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Helen Keller International, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tarini, Ann" sort="Tarini, Ann" uniqKey="Tarini A" first="Ann" last="Tarini">Ann Tarini</name>
<affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Helen Keller International, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Helen Keller International, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Epee, Emilienne" sort="Epee, Emilienne" uniqKey="Epee E" first="Emilienne" last="Epée">Emilienne Epée</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Ministry of Public Health, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Ministry of Public Health, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Biholong, Benjamin D" sort="Biholong, Benjamin D" uniqKey="Biholong B" first="Benjamin D." last="Biholong">Benjamin D. Biholong</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Ministry of Public Health, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Ministry of Public Health, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Yaobi" sort="Zhang, Yaobi" uniqKey="Zhang Y" first="Yaobi" last="Zhang">Yaobi Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Helen Keller International, Regional Office for Africa, Dakar, Senegal</addr-line>
</nlm:aff>
<country xml:lang="fr">Sénégal</country>
<wicri:regionArea>Helen Keller International, Regional Office for Africa, Dakar</wicri:regionArea>
<wicri:noRegion>Dakar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tougoue, Jean J" sort="Tougoue, Jean J" uniqKey="Tougoue J" first="Jean J." last="Tougoue">Jean J. Tougoue</name>
<affiliation wicri:level="1"><nlm:aff id="aff006"><addr-line>RTI International, Washington, D.C., United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>RTI International, Washington, D.C.</wicri:regionArea>
<wicri:noRegion>D.C.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kabore, Achille" sort="Kabore, Achille" uniqKey="Kabore A" first="Achille" last="Kabore">Achille Kabore</name>
<affiliation wicri:level="1"><nlm:aff id="aff006"><addr-line>RTI International, Washington, D.C., United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>RTI International, Washington, D.C.</wicri:regionArea>
<wicri:noRegion>D.C.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Njiokou, Flobert" sort="Njiokou, Flobert" uniqKey="Njiokou F" first="Flobert" last="Njiokou">Flobert Njiokou</name>
<affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Parasitology and Ecology Laboratory, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Parasitology and Ecology Laboratory, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kamgno, Joseph" sort="Kamgno, Joseph" uniqKey="Kamgno J" first="Joseph" last="Kamgno">Joseph Kamgno</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Centre for Research on Filariasis and other Tropical Diseases, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Centre for Research on Filariasis and other Tropical Diseases, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff007"><addr-line>Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon</addr-line>
</nlm:aff>
<country xml:lang="fr">Cameroun</country>
<wicri:regionArea>Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé</wicri:regionArea>
<wicri:noRegion>Yaoundé</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS Neglected Tropical Diseases</title>
<idno type="ISSN">1935-2727</idno>
<idno type="eISSN">1935-2735</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Albendazole (administration & dosage)</term>
<term>Animals</term>
<term>Antigens, Helminth (blood)</term>
<term>Cameroon (epidemiology)</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Communicable Disease Control (methods)</term>
<term>Disease Eradication</term>
<term>Disease Transmission, Infectious (prevention & control)</term>
<term>Elephantiasis, Filarial (epidemiology)</term>
<term>Elephantiasis, Filarial (prevention & control)</term>
<term>Elephantiasis, Filarial (transmission)</term>
<term>Female</term>
<term>Filaricides (administration & dosage)</term>
<term>Health Services Administration</term>
<term>Humans</term>
<term>Immunochromatography</term>
<term>Ivermectin (administration & dosage)</term>
<term>Male</term>
<term>Wuchereria bancrofti (isolation & purification)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Administration des services de santé</term>
<term>Albendazole (administration et posologie)</term>
<term>Animaux</term>
<term>Antigènes d'helminthe (sang)</term>
<term>Cameroun (épidémiologie)</term>
<term>Contrôle des maladies contagieuses ()</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Filaricides (administration et posologie)</term>
<term>Filariose lymphatique ()</term>
<term>Filariose lymphatique (transmission)</term>
<term>Filariose lymphatique (épidémiologie)</term>
<term>Humains</term>
<term>Immunochromatographie</term>
<term>Ivermectine (administration et posologie)</term>
<term>Mâle</term>
<term>Transmission de maladie infectieuse ()</term>
<term>Wuchereria bancrofti (isolement et purification)</term>
<term>Éradication de maladie</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Albendazole</term>
<term>Filaricides</term>
<term>Ivermectin</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigens, Helminth</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Albendazole</term>
<term>Filaricides</term>
<term>Ivermectine</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cameroon</term>
<term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Communicable Disease Control</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Disease Transmission, Infectious</term>
<term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes d'helminthe</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Cameroun</term>
<term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Disease Eradication</term>
<term>Female</term>
<term>Health Services Administration</term>
<term>Humans</term>
<term>Immunochromatography</term>
<term>Male</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Administration des services de santé</term>
<term>Animaux</term>
<term>Contrôle des maladies contagieuses</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Filariose lymphatique</term>
<term>Humains</term>
<term>Immunochromatographie</term>
<term>Mâle</term>
<term>Transmission de maladie infectieuse</term>
<term>Éradication de maladie</term>
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<front><div type="abstract" xml:lang="en"><sec id="sec001"><title>Background</title>
<p>Lymphatic filariasis (LF) is among the 10 neglected tropical diseases targeted for control or elimination by 2020. For LF elimination, the World Health Organization (WHO) has proposed a comprehensive strategy including (i) interruption of LF transmission through large-scale annual treatment (or mass drug administration (MDA)) of all eligible individuals in endemic areas, and (ii) alleviation of LF-associated suffering through morbidity management and disability prevention. In Cameroon, once-yearly mass administration of ivermectin and albendazole has been implemented since 2008. The aim of this study was to assess progress towards the elimination goal, looking specifically at the impact of six rounds of MDA on LF transmission in northern Cameroon.</p>
</sec>
<sec id="sec002"><title>Methodology</title>
<p>The study was conducted in the North and Far North Regions of Cameroon. Five health districts that successfully completed six rounds of MDA (defined as achieving a treatment coverage ≥ 65% each year) and reported no positive results for <italic>Wuchereria bancrofti</italic>
 microfilariaemia during routine surveys following the fifth MDA were grouped into three evaluation units (EU) according to WHO criteria. LF transmission was assessed through a community-based transmission assessment survey (TAS) using an immunochromatographic test (ICT) for the detection of circulating filarial antigen (CFA) in children aged 5–8 years old.</p>
</sec>
<sec id="sec003"><title>Principal findings</title>
<p>A total of 5292 children (male/female ratio 1.04) aged 5–8 years old were examined in 97 communities. Positive CFA results were observed in 2, 8 and 11 cases, with a CFA prevalence of 0.13% (95% CI: 0.04–0.46) in EU#1, 0.57% (95% CI: 0.32–1.02) in EU#2, and 0.45% (95% CI: 0.23–0.89) in EU#3.</p>
</sec>
<sec id="sec004"><title>Conclusion/Significance</title>
<p>The positive CFA cases were below WHO defined critical cut-off thresholds for stopping treatment and suggest that transmission can no longer be sustained. Post-MDA surveillance activities should be organized to evaluate whether recrudescence can occur.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Plaisier, Ap" uniqKey="Plaisier A">AP Plaisier</name>
</author>
<author><name sortKey="Stolk, Wa" uniqKey="Stolk W">WA Stolk</name>
</author>
<author><name sortKey="Van Oortmarssen, Gj" uniqKey="Van Oortmarssen G">GJ van Oortmarssen</name>
</author>
<author><name sortKey="Habbema, Jd" uniqKey="Habbema J">JD Habbema</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Michael, E" uniqKey="Michael E">E Michael</name>
</author>
<author><name sortKey="Malecela Lazaro, Mn" uniqKey="Malecela Lazaro M">MN Malecela-Lazaro</name>
</author>
<author><name sortKey="Simonsen, Pe" uniqKey="Simonsen P">PE Simonsen</name>
</author>
<author><name sortKey="Pedersen, Em" uniqKey="Pedersen E">EM Pedersen</name>
</author>
<author><name sortKey="Barker, G" uniqKey="Barker G">G Barker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stolk, Wa" uniqKey="Stolk W">WA Stolk</name>
</author>
<author><name sortKey="Swaminathan, S" uniqKey="Swaminathan S">S Swaminathan</name>
</author>
<author><name sortKey="Van Oortmarssen, Gj" uniqKey="Van Oortmarssen G">GJ van Oortmarssen</name>
</author>
<author><name sortKey="Das, Pk" uniqKey="Das P">PK Das</name>
</author>
<author><name sortKey="Habbema, Jd" uniqKey="Habbema J">JD Habbema</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Noma, M" uniqKey="Noma M">M Noma</name>
</author>
<author><name sortKey="Zoure, Hg" uniqKey="Zoure H">HG Zoure</name>
</author>
<author><name sortKey="Tekle, Ah" uniqKey="Tekle A">AH Tekle</name>
</author>
<author><name sortKey="Enyong, Pa" uniqKey="Enyong P">PA Enyong</name>
</author>
<author><name sortKey="Nwoke, Be" uniqKey="Nwoke B">BE Nwoke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zoure, Hg" uniqKey="Zoure H">HG Zoure</name>
</author>
<author><name sortKey="Noma, M" uniqKey="Noma M">M Noma</name>
</author>
<author><name sortKey="Tekle, Ah" uniqKey="Tekle A">AH Tekle</name>
</author>
<author><name sortKey="Amazigo, Uv" uniqKey="Amazigo U">UV Amazigo</name>
</author>
<author><name sortKey="Diggle, Pj" uniqKey="Diggle P">PJ Diggle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nana Djeunga, Hc" uniqKey="Nana Djeunga H">HC Nana-Djeunga</name>
</author>
<author><name sortKey="Tchatchueng Mbougua, Jb" uniqKey="Tchatchueng Mbougua J">JB Tchatchueng-Mbougua</name>
</author>
<author><name sortKey="Bopda, J" uniqKey="Bopda J">J Bopda</name>
</author>
<author><name sortKey="Mbickmen Tchana, S" uniqKey="Mbickmen Tchana S">S Mbickmen-Tchana</name>
</author>
<author><name sortKey="Elong Kana, N" uniqKey="Elong Kana N">N Elong-Kana</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Boussinesq, M" uniqKey="Boussinesq M">M Boussinesq</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Gounoue Kamkumo, R" uniqKey="Gounoue Kamkumo R">R Gounoue-Kamkumo</name>
</author>
<author><name sortKey="Nana Djeunga, Hc" uniqKey="Nana Djeunga H">HC Nana-Djeunga</name>
</author>
<author><name sortKey="Bopda, J" uniqKey="Bopda J">J Bopda</name>
</author>
<author><name sortKey="Akame, J" uniqKey="Akame J">J Akame</name>
</author>
<author><name sortKey="Tarini, A" uniqKey="Tarini A">A Tarini</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nana Djeunga, Hc" uniqKey="Nana Djeunga H">HC Nana-Djeunga</name>
</author>
<author><name sortKey="Njitchouang, Gr" uniqKey="Njitchouang G">GR Njitchouang</name>
</author>
<author><name sortKey="Tchatchueng Mbougua, Jb" uniqKey="Tchatchueng Mbougua J">JB Tchatchueng-Mbougua</name>
</author>
<author><name sortKey="Ndjomo Andjembe, Je" uniqKey="Ndjomo Andjembe J">JE Ndjomo-Andjembe</name>
</author>
<author><name sortKey="Wabo Tala, Y" uniqKey="Wabo Tala Y">Y Wabo-Tala</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Weil, Gj" uniqKey="Weil G">GJ Weil</name>
</author>
<author><name sortKey="Ramzy, Rm" uniqKey="Ramzy R">RM Ramzy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rebollo, Mp" uniqKey="Rebollo M">MP Rebollo</name>
</author>
<author><name sortKey="Bockarie, Mj" uniqKey="Bockarie M">MJ Bockarie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilson, Eb" uniqKey="Wilson E">EB Wilson</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Chu, Bk" uniqKey="Chu B">BK Chu</name>
</author>
<author><name sortKey="Deming, M" uniqKey="Deming M">M Deming</name>
</author>
<author><name sortKey="Biritwum, Nk" uniqKey="Biritwum N">NK Biritwum</name>
</author>
<author><name sortKey="Bougma, Wr" uniqKey="Bougma W">WR Bougma</name>
</author>
<author><name sortKey="Dorkenoo, Am" uniqKey="Dorkenoo A">AM Dorkenoo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ramaiah, Kd" uniqKey="Ramaiah K">KD Ramaiah</name>
</author>
<author><name sortKey="Vanamail, P" uniqKey="Vanamail P">P Vanamail</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rao, Ru" uniqKey="Rao R">RU Rao</name>
</author>
<author><name sortKey="Nagodavithana, Kc" uniqKey="Nagodavithana K">KC Nagodavithana</name>
</author>
<author><name sortKey="Samarasekera, Sd" uniqKey="Samarasekera S">SD Samarasekera</name>
</author>
<author><name sortKey="Wijegunawardana, Ad" uniqKey="Wijegunawardana A">AD Wijegunawardana</name>
</author>
<author><name sortKey="Premakumara, Wd" uniqKey="Premakumara W">WD Premakumara</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Noland, Gs" uniqKey="Noland G">GS Noland</name>
</author>
<author><name sortKey="Blount, S" uniqKey="Blount S">S Blount</name>
</author>
<author><name sortKey="Gonzalez, M" uniqKey="Gonzalez M">M Gonzalez</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Kelly Hope, La" uniqKey="Kelly Hope L">LA Kelly-Hope</name>
</author>
<author><name sortKey="Molyneux, Dh" uniqKey="Molyneux D">DH Molyneux</name>
</author>
<author><name sortKey="Bockarie, Mj" uniqKey="Bockarie M">MJ Bockarie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Richards, Fo" uniqKey="Richards F">FO Richards</name>
</author>
<author><name sortKey="Emukah, E" uniqKey="Emukah E">E Emukah</name>
</author>
<author><name sortKey="Graves, Pm" uniqKey="Graves P">PM Graves</name>
</author>
<author><name sortKey="Nkwocha, O" uniqKey="Nkwocha O">O Nkwocha</name>
</author>
<author><name sortKey="Nwankwo, L" uniqKey="Nwankwo L">L Nwankwo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Njenga, Sm" uniqKey="Njenga S">SM Njenga</name>
</author>
<author><name sortKey="Mwandawiro, Cs" uniqKey="Mwandawiro C">CS Mwandawiro</name>
</author>
<author><name sortKey="Wamae, Cn" uniqKey="Wamae C">CN Wamae</name>
</author>
<author><name sortKey="Mukoko, Da" uniqKey="Mukoko D">DA Mukoko</name>
</author>
<author><name sortKey="Omar, Aa" uniqKey="Omar A">AA Omar</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Etang, J" uniqKey="Etang J">J Etang</name>
</author>
<author><name sortKey="Pennetier, C" uniqKey="Pennetier C">C Pennetier</name>
</author>
<author><name sortKey="Piameu, M" uniqKey="Piameu M">M Piameu</name>
</author>
<author><name sortKey="Bouraima, A" uniqKey="Bouraima A">A Bouraima</name>
</author>
<author><name sortKey="Chandre, F" uniqKey="Chandre F">F Chandre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Prod Hon, J" uniqKey="Prod Hon J">J Prod'hon</name>
</author>
<author><name sortKey="Boussinesq, M" uniqKey="Boussinesq M">M Boussinesq</name>
</author>
<author><name sortKey="Fobi, G" uniqKey="Fobi G">G Fobi</name>
</author>
<author><name sortKey="Prud Hom, Jm" uniqKey="Prud Hom J">JM Prud'hom</name>
</author>
<author><name sortKey="P E" uniqKey="P E">P. E</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meredith, Seo" uniqKey="Meredith S">SEO Meredith</name>
</author>
<author><name sortKey="Cross, C" uniqKey="Cross C">C Cross</name>
</author>
<author><name sortKey="Amazigo, Uv" uniqKey="Amazigo U">UV Amazigo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Katabarwa, Mn" uniqKey="Katabarwa M">MN Katabarwa</name>
</author>
<author><name sortKey="Eyamba, A" uniqKey="Eyamba A">A Eyamba</name>
</author>
<author><name sortKey="Nwane, P" uniqKey="Nwane P">P Nwane</name>
</author>
<author><name sortKey="Enyong, P" uniqKey="Enyong P">P Enyong</name>
</author>
<author><name sortKey="Yaya, S" uniqKey="Yaya S">S Yaya</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cao, Wc" uniqKey="Cao W">WC Cao</name>
</author>
<author><name sortKey="Van Der Ploeg, Cp" uniqKey="Van Der Ploeg C">CP Van der Ploeg</name>
</author>
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<author><name sortKey="Van Der Sluijs, Ij" uniqKey="Van Der Sluijs I">IJ van der Sluijs</name>
</author>
<author><name sortKey="Habbema, Jd" uniqKey="Habbema J">JD Habbema</name>
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<author><name sortKey="Addiss, Dg" uniqKey="Addiss D">DG Addiss</name>
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<author><name sortKey="Sesay, S" uniqKey="Sesay S">S Sesay</name>
</author>
<author><name sortKey="Sonnie, M" uniqKey="Sonnie M">M Sonnie</name>
</author>
<author><name sortKey="Hodges, Mh" uniqKey="Hodges M">MH Hodges</name>
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<affiliations><list><country><li>Cameroun</li>
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<li>États-Unis</li>
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<name sortKey="Akame, Julie" sort="Akame, Julie" uniqKey="Akame J" first="Julie" last="Akame">Julie Akame</name>
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<name sortKey="Domche, Andre" sort="Domche, Andre" uniqKey="Domche A" first="André" last="Domche">André Domche</name>
<name sortKey="Domche, Andre" sort="Domche, Andre" uniqKey="Domche A" first="André" last="Domche">André Domche</name>
<name sortKey="Epee, Emilienne" sort="Epee, Emilienne" uniqKey="Epee E" first="Emilienne" last="Epée">Emilienne Epée</name>
<name sortKey="Kamgno, Joseph" sort="Kamgno, Joseph" uniqKey="Kamgno J" first="Joseph" last="Kamgno">Joseph Kamgno</name>
<name sortKey="Kamgno, Joseph" sort="Kamgno, Joseph" uniqKey="Kamgno J" first="Joseph" last="Kamgno">Joseph Kamgno</name>
<name sortKey="Mbickmen Tchana, Steve" sort="Mbickmen Tchana, Steve" uniqKey="Mbickmen Tchana S" first="Stève" last="Mbickmen-Tchana">Stève Mbickmen-Tchana</name>
<name sortKey="Nana Djeunga, Hugues C" sort="Nana Djeunga, Hugues C" uniqKey="Nana Djeunga H" first="Hugues C." last="Nana-Djeunga">Hugues C. Nana-Djeunga</name>
<name sortKey="Njiokou, Flobert" sort="Njiokou, Flobert" uniqKey="Njiokou F" first="Flobert" last="Njiokou">Flobert Njiokou</name>
<name sortKey="Njitchouang, Guy R" sort="Njitchouang, Guy R" uniqKey="Njitchouang G" first="Guy R." last="Njitchouang">Guy R. Njitchouang</name>
<name sortKey="Nwane, Philippe" sort="Nwane, Philippe" uniqKey="Nwane P" first="Philippe" last="Nwane">Philippe Nwane</name>
<name sortKey="Tarini, Ann" sort="Tarini, Ann" uniqKey="Tarini A" first="Ann" last="Tarini">Ann Tarini</name>
<name sortKey="Tchatchueng Mbougua, Jules B" sort="Tchatchueng Mbougua, Jules B" uniqKey="Tchatchueng Mbougua J" first="Jules B." last="Tchatchueng-Mbougua">Jules B. Tchatchueng-Mbougua</name>
<name sortKey="Tchouakui, Magellan" sort="Tchouakui, Magellan" uniqKey="Tchouakui M" first="Magellan" last="Tchouakui">Magellan Tchouakui</name>
<name sortKey="Tchouakui, Magellan" sort="Tchouakui, Magellan" uniqKey="Tchouakui M" first="Magellan" last="Tchouakui">Magellan Tchouakui</name>
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<country name="Sénégal"><noRegion><name sortKey="Zhang, Yaobi" sort="Zhang, Yaobi" uniqKey="Zhang Y" first="Yaobi" last="Zhang">Yaobi Zhang</name>
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<country name="États-Unis"><noRegion><name sortKey="Tougoue, Jean J" sort="Tougoue, Jean J" uniqKey="Tougoue J" first="Jean J." last="Tougoue">Jean J. Tougoue</name>
</noRegion>
<name sortKey="Kabore, Achille" sort="Kabore, Achille" uniqKey="Kabore A" first="Achille" last="Kabore">Achille Kabore</name>
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</record>

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   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
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   |clé=     PMC:5490934
   |texte=   First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination
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Serveur d'exploration sur le lymphœdème

First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination

First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination

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	Serveur d'exploration sur le lymphœdème
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